The Nano particulate systems indicates the enhanced drug delivery to brain as compared to the drug solution formulation through avoidance Method through which the drug can be delivered to brain throughīypassing of BBB. The intranasal drug delivery is the noninvasive The direct drugĭelivery of drugs to brain may indicate higher therapeutic activity to toxicity The effective treatment and diagnosis of various CNS diseases is restricted byīlood–Brain Barrier (BBB) which inhibits almost all the macromolecular drugsĪs well as small-molecule drugs to permeate through brain. Imaging agents with the effective drug targeting at required site in the body. Systems such as dendrimers, lipoic nanoparticles, inorganic nanoparticlesĪnd polymeric nanoparticles capable of incorporating the therapeutic drugs or There are various Nano particulate drug delivery The drugs which are used for the treatment of are bacterial meningitis areĪmpicillin, gentamycin, cefotaxime, and vancomycin HCL, where vancomycin
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This open-access article is distributed under the terms of the Creative Commons Attribution Non-Commercial License (CC BY-NC) (), which permits reuse, distribution and reproduction of the article, provided that the original work is properly cited and the reuse is restricted to noncommercial purposes. Formulation Development and Evaluation of Vancomycin HCL Nanoparticles for the Treatment of Bacterial Meningitis. Received Date: / Accepted Date: / Published Date: Sep 29, 2021Ĭitation: Athalye M, Patel A. College of Pharmacy, Navrangpura, Ahmedabad, Gujarat,
Department of Pharmaceutics and Pharmaceutical Technology,